Antioxidants – substances that inhibit oxidative changes in molecules. Many oxidative changes are destructive and this applies as much to the human body as to non-biological chemistry. Recognition that many of the fundamentally damaging processes in disease are oxidative in nature and result from the action of oxygen FREE RADICALS has raised interest in the possibility of using antioxidants to minimize such damage. The most popular choice for this purpose are the antioxidant vitamins C and E. There is evidence that, taken in adequate dosage, these vitamins act synergistically to reduce free radical effects. See also FLAVONOIDS and FRENCH PARADOX.